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目的 :探讨腹腔热化疗治疗癌性腹腔积液的临床疗效和毒副作用。方法 :将 6 0例癌性腹水病人随机分成两组 :腹腔热化疗组和腹腔化疗组 ,每组 30例 ,化疗方案为FP方案 ( 5 FU和DDP)。结果 :腹腔热化疗组有效率为 83 .3 % ,腹腔化疗组有效率为5 6 .7% ,两组统计学上有明显差异 (P <0 .0 5 )。结论 :腹腔热化疗是治疗癌性腹腔积液较有效的方法之一 ,值得临床推广。
Objective: To investigate the clinical efficacy and side effects of intraperitoneal hyperthermia in the treatment of malignant ascites. Methods: Sixty patients with cancerous ascites were randomly divided into two groups: peritoneal thermotherapy group and intraperitoneal chemotherapy group, 30 cases in each group. The chemotherapy regimen was FP regimen (5 FU and DDP). Results: The effective rate of peritoneal thermotherapy group was 83.3%, the effective rate of intraperitoneal chemotherapy group was 56.7%, there was significant difference between the two groups (P <0.05). Conclusion: Intraperitoneal thermochemotherapy is one of the more effective methods for the treatment of malignant ascites, which is worthy of clinical promotion.