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目的探讨缓释顺铂瘤体植入联合放疗对原发性肝癌的短期疗效。方法治疗前选择已经确诊的原发性肝癌,随机分为治疗组(药物植入+放疗)和对照组(单纯放疗),主要根据瘤体大小决定植入药量,观察期限2月,统计两组临床获益率ORR(CR+PR+SD=ORR)。结果治疗组和对照组ORR分别为87.50%和57.50%(χ2=21.67,P<0.05)。结论缓释顺铂瘤体植入合并放疗治疗原发性肝癌能提高近期疗效。
Objective To investigate the short-term curative effect of slow-release cisplatin tumor combined with radiotherapy on primary liver cancer. Methods The patients with confirmed primary hepatocellular carcinoma before treatment were randomly divided into treatment group (drug implantation + radiotherapy) and control group (radiotherapy alone). The dosage was determined mainly according to the size of the tumor. The observation period was 2 months, Group clinical benefit rate ORR (CR + PR + SD = ORR). Results The ORR of the treatment group and the control group were 87.50% and 57.50% (χ2 = 21.67, P <0.05). Conclusion The slow release cisplatin tumor implantation combined with radiotherapy for the treatment of primary liver cancer can improve the short-term efficacy.