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营养不良常见于慢性阻塞性肺病(CAPD)患者。观察47例COPD呼吸衰竭患者的有关营养指标。结果显示:治疗前两组体重均低于理想体重(IBW),血清蛋白低于正常值,支链氨基酸(BCAA)/芳香族氨基酸(AAA)下降,TLC和CD_4/CD_8降低。急性期前白蛋白(PALB)和a_1-AT呈正相关(r=0.386,P<0.05)。经2周营养治疗后,上述指标营养组较常规组改善明显。提示:COPD呼吸衰竭患者存在着营养不良,营养不良影响了免疫功能和呼吸肌功能。营养治疗能改善COPD呼吸衰竭患者的预后。
Malnutrition is common in patients with chronic obstructive pulmonary disease (CAPD). Observe 47 patients with COPD respiratory failure related nutritional indicators. The results showed that body weight of the two groups before treatment was lower than ideal body weight (IBW), serum protein was lower than normal, BCAA / AAA decreased, TLC and CD_4 / CD_8 decreased. Acute prealbumin (PALB) and a_1-AT were positively correlated (r = 0.386, P <0.05). After 2 weeks of nutrition treatment, the above indicators of nutrition group improved significantly than the conventional group. TIP: Malnutrition exists in COPD patients with respiratory failure and malnutrition affects both immune function and respiratory muscle function. Nutritional therapy can improve the prognosis of COPD patients with respiratory failure.