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目的探讨医用几丁糖用于预防人工流产术后宫腔粘连的效果。方法选取2015年6月至2017年1月于惠州市惠阳区妇幼保健院行人工流产手术的180例患者作为研究对象,按照预防人工流产术后宫腔粘连方法的不同分为观察组与对照组,各90例。人工流产术后观察组患者给予常规治疗联合医用几丁糖预防宫腔粘连,对照组患者仅给予常规治疗,比较两组患者临床指标改善情况、月经情况、宫腔粘连发生情况及术后感染发生情况。结果观察组患者阴道流血时间、腹痛持续时间均明显短于对照组,阴道流血量显著少于对照组,差异均有统计学意义(均P<0.05);观察组术后月经正常患者比例明显高于对照组,差异有统计学意义(P<0.05);观察组术后患者宫腔粘连发生率明显低于对照组,差异有统计学意义(P<0.05);观察组患者术后未发生感染情况,对照组感染16例,感染率为17.8%,组间比较差异有统计学意义(χ2=6.698,P<0.05)。结论医用几丁糖预防人工流产术后宫腔粘连发生的效果显著,在改善患者术后临床症状的同时还可促进月经恢复,降低术后感染风险。
Objective To investigate the effect of medical chitosan on prevention of intrauterine adhesions after induced abortion. Methods 180 patients with induced abortion in Huiyang District Maternity and Child Care Hospital of Huizhou City from June 2015 to January 2017 were selected as the research objects and divided into observation group and control group according to the method of preventing intrauterine adhesions after induced abortion , 90 cases each. The patients in the observation group were given conventional therapy combined with medical chitosan to prevent intrauterine adhesions, the patients in the control group were given routine treatment only. The improvement of clinical indexes, menstruation, intrauterine adhesions and postoperative infection were compared between the two groups Happening. Results The duration of vaginal bleeding and the duration of abdominal pain in the observation group were significantly shorter than those in the control group, and the amount of vaginal bleeding was significantly less than that in the control group (all P <0.05). The proportion of normal menstruation patients in the observation group was significantly higher (P <0.05). The incidence of intrauterine adhesions in the observation group was significantly lower than that in the control group (P <0.05). No postoperative infection was found in the observation group In the control group, 16 cases were infected and the infection rate was 17.8%. The difference between the two groups was statistically significant (χ2 = 6.698, P <0.05). Conclusion The clinical effect of chitosan for prevention of intrauterine adhesions after induced abortion is significant. It can promote the recovery of menstruation and reduce the risk of postoperative infection while improving the clinical symptoms.