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作者在3年期间共随访65例慢性活动性肝炎和2例乙肝病毒引起的肝硬化,发现7例(其中慢活肝5例,肝硬化2例)在携带HBsAg2～14年后HBsAg转阴,4例抗-HBs转为阳性。在HBsAg从血中消失后,肝内便不再有持续性炎症存在。7例病人中有5例曾接受1～39个月的强的松龙,有时联合硫唑嘌呤的治疗,但在最后一次检测HBsAg前上述药物已停用3年余,因此可除外这些药物的影响。作者认为,即使在长期病程
A total of 65 patients with chronic active hepatitis and 2 hepatitis B virus-induced cirrhosis were followed up over a 3-year period. Seven patients (5 with slow-survival liver and 2 with cirrhosis) were found to be HBsAg negative after 2 to 14 years of HBsAg, 4 cases of anti-HBs turned positive. After HBsAg disappears from the blood, there is no longer persistent inflammation in the liver. Five of the seven patients had had prednisolone 1 to 39 months, sometimes in combination with azathioprine, but the drug was discontinued for more than three years before the last HBsAg test, influences. The authors believe that even in the long term course