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目的:探讨酒精性肝硬化与肝炎后肝硬化的临床特点。方法:对60例酒精性肝硬化患者与同期住院的肝炎后肝硬化患者为对照进行回顾性分析。结果:酒精性肝硬化辅助检查示谷氨酸基转移酶(GGT)升高,天冬氨酸氨基转移酶(AST)/血清丙氨酸基转移酶(ALT)血尿酸(UA)等升高明显,肝大、脂肪肝、胆囊炎、胆石症、胰腺炎发生比例较肝炎后肝硬化高,与肝炎后肝硬化比较差异显著(P<0.05)。结论:酒精性肝硬化患者的血清GGT升高显著。提示GGT是反映酒精性肝硬化的特征性指标。酒精性肝硬化预后比肝炎后肝硬化好,但晚期二者预后差别不大。因此,早发现、早诊断、早治疗可明显改善酒精性肝硬化患者的预后。
Objective: To investigate the clinical features of alcoholic cirrhosis and cirrhosis after hepatitis. Methods: A retrospective analysis of 60 patients with alcoholic cirrhosis and hospitalized patients with posthepatitic cirrhosis. Results: In alcoholic cirrhosis, elevated GGT, elevated serum AST and serum UA were observed Obviously, the incidence of hepatomegaly, fatty liver, cholecystitis, cholelithiasis and pancreatitis is higher than that of post-hepatitis cirrhosis, and is significantly different from post-hepatitis cirrhosis (P <0.05). Conclusion: Serum GGT in patients with alcoholic liver cirrhosis increased significantly. Tip GGT is a characteristic indicator of alcoholic cirrhosis. The prognosis of alcoholic cirrhosis than hepatitis cirrhosis, but the prognosis of late little difference between the two. Therefore, early detection, early diagnosis, early treatment can significantly improve the prognosis of patients with alcoholic liver cirrhosis.