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目的探讨白内障手术围术期抗菌药物预防性。方法随机抽取本院眼科2013年7月至12月出院白内障手术患者共190例,对其进行评价。结果 190份符合条件的病历,所有患者在手术后均未出现感染病例,全部的切口均为甲级愈合。无1例联用2种以上抗菌药物情况,2例(1.1%)使用1种抗菌药物,188例(99.0%)使用2种抗菌药物。本组全部患者都局部使用抗菌药物,其中6例(3.2%)单独使用氯霉素滴眼液,50例(26.3%)单独使用妥布霉素地塞米松滴眼液,18例(9.5%)单独使用左氧氟沙星滴眼液,116例(61.0%)采用妥布霉素地塞米松滴眼液+盐酸洛美沙星滴眼液联用。全部患者局部使用抗菌药物的开始时间为术前1~2 d,术后局部使用抗菌药物7~12 d。所有手术术毕采用四环素眼膏涂眼。结论为预防白内障术后感染眼内炎,应合理使用局部抗菌药物,加强围术期无菌操作,掌握合理应用抗菌药物的基本知识,重视病原学检查,以减少甚至杜绝术后感染的发生。
Objective To investigate the perioperative antimicrobial prophylaxis of cataract surgery. Methods A total of 190 cases of cataract discharged from our hospital from July 2013 to December 2013 were selected and evaluated. Results 190 eligible medical records, all patients were not infected after surgery cases, all the incisions are grade A healing. No combination of two or more antimicrobial agents was used in one case, one antimicrobial agent was used in two cases (1.1%) and two antimicrobials were used in 188 cases (99.0%). Antibiotics were topically applied to all patients in this study, including 6 (3.2%) chloramphenicol alone, 50 (26.3%) tobramycin dexamethasone alone, and 18 (9.5% ) Alone levofloxacin eye drops, 116 cases (61.0%) with tobramycin dexamethasone eye drops + lomefloxacin hydrochloride eye drops combined. All patients with local antibacterial drugs started 1 to 2 days before surgery, followed by topical use of antimicrobial drugs for 7 to 12 days. All surgical use of tetracycline eye ointment coated eyes. Conclusion In order to prevent endophthalmitis infection after cataract surgery, local antimicrobial agents should be used reasonably to enhance the perioperative aseptic operation, to master the basic knowledge of rational use of antimicrobial agents and to pay attention to the etiological examination to reduce or even eliminate the postoperative infection.