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美国加利福尼亚大学医学院Kalmansohn最近报导10家医院11名研究者的一项对照研究用Disopyramide phosphate治疗120例心律失常患者,89例获得良好至极好的疗效。 120例中,48例为多灶性室性期前收缩(PVC’S);29例为单灶性PVC’S;18例为PVC’S加房性期前收缩(PAC);4例为PVC’S加房性阵发性心动过速(PAT);1例PAT;18例PVC’S加PAC加PAT;2例PAC加PAT。判断疗效的标准为治疗期间每一动态心电图记录显示异位搏动比最佳安慰剂反应至
Kalmansohn of the University of California School of Medicine recently reported a control study of 11 researchers in 10 hospitals using Disopyramide phosphate in 120 patients with arrhythmias and 89 patients achieving good to excellent results. Of the 120 cases, 48 were multifocal ventricular premature contractions (PVC’s), 29 were single-staged PVC’s, 18 were PVC’s plus atrial premature contractions (PACs), and 4 were PVC’S plus atrial burst Tachycardia (PAT); 1 case of PAT; 18 cases of PVC’S plus PAC plus PAT; 2 cases of PAC plus PAT. Criteria for assessing efficacy were recorded for each ambulatory electrocardiogram during the treatment period. Ectopic beats responded better than placebo to