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[目的]了解基因乙肝疫苗的免疫效果。[方法]对1 869名HBsAg阴性的人群按0、1、6方案接种基因乙肝疫苗,接种6个月后取静脉血用ELISA法检测HBsAb和HBsAg。[结果]全程免疫后,HBsAb的阳转率为72.2%(1349/1 869);10~19岁年龄组的HBsAb阳转率最高,50岁以上者阳转率最低,HBsAb阳转率与年龄有关。[结论]所使用的2种疫苗阳转率类似(2=0.21,P>0.05)。
[Objective] To understand the immune effect of gene hepatitis B vaccine. [Method] A total of 1 869 HBsAg-negative patients were vaccinated with gene hepatitis B vaccine according to the 0, 1, and 6 regimens. After 6 months of inoculation, venous blood was collected for detection of HBsAb and HBsAg by ELISA. [Results] The positive rate of HBsAb was 72.2% (1349/1 869) after full immunization. The positive rate of HBsAb in the 10-19 age group was the highest, while the positive rate of HBsAb was the lowest in those over 50 years old. related. [Conclusion] The positive rates of the two vaccines used were similar (2 = 0.21, P> 0.05).