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目的分析总结124例不明原因发热(FUO)患者的病因,指导临床FUO诊断。方法对124例“发热原因待查”患者的临床表现及诊疗资料进行回顾性分析。结果 124例中最后确诊116例,确诊率为93.5%。确诊的116例患者中感染性疾病59例,占50.9%,其中普通细菌感染及结核感染居多,其次为寄生虫病及病毒感染,非感染性疾病57例,占49.1%,其中肿瘤占29.3%(34/116),风湿结缔组织病占17.2%(20/116)。结论 FUO的病因中,感染性疾病的发病略高于非感染性疾病,普通细菌感染、结核菌感染、恶性肿瘤(特别是造血系统恶性肿瘤)、结缔组织病所致发热是FUO的常见原因,一些寄生虫病及病毒感染也应引起足够的重视,避免误诊。
Objective To summarize the causes of 124 patients with unexplained fever (FUO), and to guide the clinical diagnosis of FUO. Methods A retrospective analysis was performed on the clinical manifestations and diagnosis and treatment data of 124 patients with fever whose cause of investigation was to be investigated. Results The final diagnosis of 124 cases of 116 cases, the diagnosis rate was 93.5%. Of the 116 confirmed cases, 59 were infectious diseases, accounting for 50.9% of them. Among them, common bacterial infections and tuberculosis infections were most common, followed by parasitic diseases and viral infections. Non-infectious diseases were 57 cases (49.1%), of which 29.3% (34/116), rheumatic connective tissue disease accounted for 17.2% (20/116). Conclusions Among the causes of FUO, the incidence of infectious diseases is slightly higher than that of non-infectious diseases, common bacterial infections, tuberculosis infections, malignant tumors (especially hematopoietic malignancies), and fever caused by connective tissue disease, which are common causes of FUO. Some parasitic diseases and viral infections should also attract enough attention to avoid misdiagnosis.