多发性骨髓瘤发病较少,由于临床无特异性,起病隐袭,容易误诊。本例多次求诊于省级医院,却误诊达两年之久。为吸取教训现将误诊原因分析如下。病历摘要女患,60岁。78年春起无诱因出现双手指骨及双小腿骨酸痛。同年10月双手指骨疼痛加重,活动如针刺样痛,压痛明显,伴有前胸及后背酸痛。但关节无肿胀及畸型。摄指骨片显示骨质疏松,诊为 Multiple myeloma less incidence, due to clinical non-specific, insidious onset, easy misdiagnosis. In this case multiple visits in the provincial hospital, but misdiagnosed for two years. The reasons for misdiagnosis are now analyzed as follows. Female patient history, 60 years old. There is no incentive in 78 years since the emergence of both hands, phalanges and phalanges bone pain. In October the same year, both hands phalanx ache aggravated, activities such as acupuncture-like pain, tenderness, accompanied by chest and back pain. However, no swelling and abnormal joints. Finger phalanx showed osteoporosis, diagnosed as