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通常在考虑影响十二指肠溃疡愈合的因素时,往往重视药物的作用而忽视药物以外的因素。本文对108例经内窥镜证实的十二指肠溃疡患者,于6～12个月后作内窥镜复查,66例(61%)溃疡愈合。分析影响溃疡愈合的因素可能为:男性,经济条件差,近期上腹痛、夜间痛和背痛,吸烟,饮酒,溃疡旁炎症和十二指肠球腔狭窄等。如将上述因素每一种计为1分,进行积分,可见随着积分的升高,溃疡愈合率明显降低。显然,认识上述各种不利因素对于有效治疗和判断预后是至为重要的。
Often when considering the factors that affect the healing of duodenal ulcers, emphasis is placed on the role of the drug while ignoring factors other than drugs. In this article, 108 cases of endoscopically confirmed duodenal ulcer patients were reexamined after 6 to 12 months. 66 (61%) ulcers healed. Analysis of factors affecting ulcer healing may be: men, poor economic conditions, recent epigastric pain, nocturnal and back pain, smoking, alcohol consumption, para-ulcer inflammation and duodenal stenosis. If each of the above factors is counted as 1 and the score is integrated, it can be seen that with the increase of the integral, the ulcer healing rate is significantly reduced. Obviously, understanding the above-mentioned various unfavorable factors is very important for effective treatment and judgment of prognosis.