引言干细胞具有自我更新能力和向多种分化的潜能,其中造血干细胞向多种血细胞分化及造血干细胞移植对某些血液病的治疗作用已被认识和熟悉,近年来研究认为,肠道也存在干细胞,且肠道干细胞研究取得了一些进展,肠道干细胞可分化为肠上皮的所有细胞系,参与正常肠黏膜组织更新的生理过程及一些病理过程.迄今国内对肠道干细胞的研究报道较少,本文复习了近年来国外有关肠道干细胞研究的文献并综述如下: Introduction Stem cells have the ability of self-renewal and differentiation to a variety of differentiation, of which hematopoietic stem cells to a variety of blood cells and hematopoietic stem cell transplantation for the treatment of certain blood diseases have been recognized and familiar with, in recent years, studies have suggested that there are also intestinal stem cells , And some progresses have been made in the study of gut stem cells, which can differentiate into all cell lines of the gut epithelium, and participate in the physiological processes and some pathological processes of normal intestinal mucosa renewal. So far, there are few reports on gut stem cells in China, This review of the recent literature on intestinal stem cells abroad and summarized as follows: