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目的 观察蚓激酶联合前列地尔 (PGE1)对周围动脉粥样硬化闭塞症 (ASO)的治疗效果。方法 选择 6 2例ASO患者 ,随机分为蚓激酶联合前列地尔、常规PGE1治疗两组 ,动态观察临床表现 ,同时采用超声检查测定治疗前后踝肱指数和动脉狭窄程度的改变。结果 蚓激酶联合前列地尔组临床治疗优良率是93 5 % ,优于常规PGE1组 ( 71% ) (P <0 0 5 )。结论 蚓激酶联合前列地尔治疗ASO具有较好的临床疗效。
Objective To observe the therapeutic effect of lumbrokinase combined with prostaglandin (PGE1) on peripheral atherosclerosis obliterans (ASO). Methods Sixty ASO patients were selected and randomly divided into Lumbrokinase combined with alprostadil and conventional PGE1 treatment. The clinical manifestations were observed dynamically. The changes of ankle brachial index and arterial stenosis before and after treatment were also measured by ultrasound. Results The excellent and good rate of clinical treatment of lumbrokinase combined with alprostadil group was 93.5%, which was better than that of PGE1 group (71%) (P <0.05). Conclusion Lumbrokinase combined with alprostadil has good clinical efficacy in the treatment of ASO.