摘要目的比较吸气相及呼气相肺叶通气CT数据与超极化3He-MR成像上直接测量的肺通气数据,利用与3HeMR成像相同屏气时段所获得的1H-MR成像来配准多模态影像。材料与方法本研究经国家研究伦理委员会批准,并获得病人书面同意。30例哮喘病人在总肺容量及功能余气量的状态下屏气行CT检查。在功能余气量加上1 L的肺容量状态下相同屏气时段获得3He-MR和1H-MR影像。通过主 Abstract Objective To compare the lung ventilation data of inspiratory and expiratory leaflet ventilation CT data and hyperpolarised 3He-MR imaging directly with 1H-MR imaging obtained during the same breath-holding time period as 3HeMR imaging to register multimodality image. Materials and Methods The study was approved by the National Research Ethics Committee with the written consent of the patients. Thirty patients with asthma underwent breath-hold CT examination with total lung capacity and functional residual capacity. The 3He-MR and 1H-MR images were obtained during the same breath-hold period with a functional capacity plus 1 L of lung capacity. Through the Lord