论文部分内容阅读
目的调查分析拉萨市藏、汉民族间血脂水平及其异常检出率的差异,为该地区血脂异常症的预防提供客观依据。方法选取拉萨市藏(Tibetan,T)、汉民族(Han,H)1 228例体检人群为调查对象,其中藏族559例,汉族669例,按血脂测定标准化方法测定的血清总胆固醇(total cholesterol,TC)、三酰甘油(triglycerin,TG)、高密度脂蛋白胆固醇(high-density lipoprotein cholesterol,HDL-C)及低密度脂蛋白胆固醇(low-density lipoproteincholesterol,LDL-C)4项指标的血脂水平;按2007年《中国成人血脂异常防治指南》将研究对象分为4个年龄组,界定4项血脂异常标准值,比较藏、汉民族各年龄组血脂异常检出率的差异。采用协方差分析和χ2检验比较两民族间血脂存在的差异。结果汉族TG水平高于藏族(P≤0.001),HDL-C水平低于藏族(P<0.001);藏族TC和LDL-C水平均高于汉族(P<0.001、P=0.013)。藏族男性青年组、中年组、老年前期组TC异常检出率均显著高于汉族(P<0.001),藏族男性中年组和女性青年组、中年组TG异常检出率反而比汉族高(P<0.001、P<0.05、P<0.001);汉族男性青年组、中年组、老年前期组HDL-C异常检出率明显高于藏族(P<0.001)。结论藏族是混合型高脂血症的高危人群,尤其藏族男性;汉族男性是低HDL-C血症的高危人群。
Objective To investigate the differences of blood lipid levels and the abnormal detection rates between Tibetans and Han nationalities in Lhasa, and provide an objective basis for the prevention of dyslipidemia in this region. Methods A total of 1 228 Han nationality medical exams were selected from Lhasa Tibetan Autonomous Prefecture (Han, H), of which 559 were Tibetan and 669 were Han nationality. Total cholesterol (total cholesterol, TC, triglycerin (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) According to the 2007 Guidelines for the Prevention and Treatment of Dyslipidemia in Chinese Adults, the subjects were divided into four age groups and four standard values of dyslipidemia were defined. The differences in the detection rates of dyslipidemia between Tibetans and Han were compared. Covariance analysis and χ2 test were used to compare the differences in blood lipids between the two ethnic groups. Results The levels of TG and LDL-C in Han were higher than those in Tibetan (P≤0.001) and HDL-C (P <0.001). The levels of TC and LDL-C in Tibetan were higher than Han (P <0.001, P = 0.013). The detection rate of TC anomaly in Tibetan male youth group, middle-aged group and pre-elderly group were significantly higher than that in Han (P <0.001). The detection rate of TG abnormality in middle-aged Tibetan male middle-aged group and young female group was higher than that in Han nationality (P <0.001, P <0.05, P <0.001). The detection rate of abnormal HDL-C in Han male, middle-aged and pre-elderly groups was significantly higher than that in Tibetan (P <0.001). Conclusion Tibetan is a high risk group with mixed hyperlipidemia, especially Tibetan males; Han males are high risk groups with low HDL-C.