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目的 观察鱼腥草联合贝复舒 (b FGF滴眼液 )对复发性单纯疱疹性角膜炎的疗效。方法 治疗组 30例用鱼腥草注射液静脉滴注、点眼及贝复舒点眼 ,对照组 2 9例用无环鸟苷注射液静脉滴注联合局部点眼 ,随访 1~2年 ,平均为 15月。结果 治疗组痊愈率为 86 .6 2 % ,有效率为 93.33% ,与对照组痊愈率 5 1.72 %和有效率6 9.0 7%比较 ,差异有显著意义 (P <0 .0 5 ) ;平均治愈天数治疗组 (18.2 1± 2 .4 5天 )少于对照组 (2 0 .36± 2 .2 3天 )(P <0 .0 1) ;随访病例治疗组 2 6例 ,复发 1例 ,复发率为 3.85 % ,对照组 15例 ,复发 5例 ,复发率为 33.33% ,两组比较 ,差异有显著意义 (P <0 .0 5 )。结论 鱼腥草联合贝复舒可提高复发性单纯疱疹性角膜炎的治愈率 ,缩短疗程 ,并有利于角膜组织最佳修复 ,不留或少留瘢痕 ,对预防和减少复发及其它并发症也有积极作用
Objective To observe the curative effect of Houttuynia combined with bFGF eye drops on recurrent herpes simplex keratitis. Methods Thirty patients in the treatment group were treated with Houttuynia Cordata injection intravenously and instilled at both eyes and in Beifu Shu. The control group received intravenous infusion of acyclovir injection for local eye contact. The patients were followed up for 1-2 years with an average of 15 month. Results The cure rate in the treatment group was 86.62%, the effective rate was 93.33%, which was significantly different from the control group with the cure rate of 5.72% and the effective rate of 6 9.07% (P <0.05); the average cure rate (18.21 ± 2.45 days) in the treatment group was less than that in the control group (20.36 ± 2.23 days) (P <0.01). In the follow-up cases, 26 cases were treated and 1 case was relapsed, The recurrence rate was 3.85%, 15 cases in the control group, 5 cases relapsed, the recurrence rate was 33.33%. There was significant difference between the two groups (P <0.05). Conclusion Houttuynia combined with Beifu Shu can improve the cure rate of recurrent herpes simplex keratitis, shorten the course of treatment, and is conducive to the best corneal tissue repair, leaving no or less scarring, to prevent and reduce recurrence and other complications positive effects