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目前我国人口老龄化速度较快,从第五次全国人口普查的结果来看,我国65岁以上人口(8811万人)占总人口的6.96%。我国帕金森病(PD)的患病率也随人口老龄化而明显增高。PD 是一种慢性进展性神经系统疾病。它严重损害老年人的身体健康和影响老年人的日常生活,并给家庭和社会带来经济上沉重的负担。近30余年来,对 PD的发病机制和治疗的研究已获得了较大的突破。近年来,世界各国科学家都在进行有关 PD 的实验室研究、遗传学研究、免疫学研究、影像学研究等,现综述如下。1 PD 的实验研究
At present, China’s population is aging at an accelerated rate. According to the results of the fifth national census, the population over 65 years of age (88.11 million) in China accounts for 6.96% of the total population. The prevalence of Parkinson’s disease (PD) in our country is also obviously increased with the population aging. PD is a chronic progressive neurological disease. It seriously damages the health of the elderly and affects the daily lives of older persons and places an extremely heavy financial burden on families and communities. For more than 30 years, the research on the pathogenesis and treatment of PD has made a big breakthrough. In recent years, scientists from all over the world are conducting laboratory research on PD, genetics research, immunology research, imaging research, are summarized below. 1 PD experimental study