论文部分内容阅读
目的研究美托洛尔与胺碘酮联合应用治疗快速性心律失常的效果及和安全性。方法 132例快速性心律失常患者,随机分为对照组和试验组,各66例。对照组患者应用胺碘酮治疗,试验组患者应用胺碘酮与美托洛尔联合治疗。比较两组患者显效率、心率情况和不良反应发生率。结果试验组患者显效率为93.9%,对照组患者显效率为77.3%,两组比较差异有统计学意义(P<0.05);治疗前两组心率比较,差异无统计学意义(P>0.05);治疗后试验组心率远低于对照组,差异有统计学意义(P<0.05)。试验组患者不良反应发生率为6.1%,对照组患者不良反应发生率为4.5%,比较差异无统计学意义(P>0.05)。结论美托洛尔与胺碘酮联合应用治疗快速性心律失常临床效果确切,有助于恢复正常的心率,不良反应轻,较胺碘酮单独治疗效果更优,具有广阔的临床应用前景。
Objective To study the efficacy and safety of metoprolol combined with amiodarone in the treatment of tachyarrhythmia. Methods A total of 132 patients with tachyarrhythmia were randomly divided into control group and trial group, with 66 cases in each group. Patients in the control group were treated with amiodarone. Patients in the test group were treated with amiodarone combined with metoprolol. Significant efficiency, heart rate and incidence of adverse reactions were compared between the two groups. Results The markedly effective rate was 93.9% in the test group and 77.3% in the control group, with significant difference between the two groups (P <0.05). There was no significant difference in heart rate between the two groups before treatment (P> 0.05) After treatment, the heart rate of the experimental group was much lower than that of the control group, with significant difference (P <0.05). The incidence of adverse reactions in the trial group was 6.1%, while the incidence of adverse reactions in the control group was 4.5%, with no significant difference (P> 0.05). Conclusion Metoprolol combined with amiodarone in the treatment of tachyarrhythmia clinical effect is exact, helps to restore normal heart rate, adverse reactions, more effective than amiodarone alone treatment, has a broad clinical application prospects.