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对随机放置ＭＬ３７５、Ｆｉｎｃｏｉｄ３５０、ＴＣｕ２２０ｃ和镀铜宫腔形ＩＵＤ（ＵＣＤＣｕ）各１００例，临床观察３年，随访率９９．７５％。研究结果表明：４种ＩＵＤ的妊娠率分别为３．１９％、５．２８％、２．１６％及３．０９％，其中Ｆｉｎｃｏｉｄ３５０最高，ＴＣｕ２２０ｃ最低，各组间差异无显著性意义（Ｐ＞０．０５）；脱落率为３．１４％、６．４４％、５．１６％及２．０７％，其中Ｆｉｎｃｏｉｄ３５０最高，ＵＣＤＣｕ最低，两者间相比无显著性差异（Ｐ＞０．０５）；因症取出率分别为４．０６％、８．９９％、３．０７％及１．０３％，ＴＣｕ２２０ｃ和ＵＣＤＣｕ的因症取出率明显低于Ｆｉｎｃｏｉｄ３５０，皆有显著性意义（Ｐ＜０．０５）；粗累积续用率分别为８９．００％、７９．８４％、９０．００％及９３．９４％，ＵＣＤＣｕ明显高于Ｆｉｎｃｏｉｄ３５０，且有极显著性意义（Ｐ＜０．０１）。
100 cases of ML375, Fincoid350, TCu220c and copper-coated uterine cavity IUD (UCDCu) were randomly placed. The clinical observation was 3 years and the follow-up rate was 99.75%. The results showed that the pregnancy rates of the 4 kinds of IUDs were 3.19%, 5.28%, 2.16% and 3.09%, respectively. The highest Fincoid350 and the lowest TCu220c were found among the 4 groups (P> 0.05). The shedding rates were 3.14%, 6.44%, 5.16% and 2.07%, respectively. The highest Fincoid 350 and the lowest UCDCu were found (P> 0.05 ). The removal rates of TCu220c and UCDCu were significantly lower than those of Fincoid350 (4.06%, 8.99%, 3.07% and 1.03%, respectively) (P <0.01). UCDCu was significantly higher than that of Fincoid350 (89.00%, 79.84%, 90.00% and 93.94%, respectively) .