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目的观察头低位卧床模拟失重期间脑电信号复杂度的变化,研究脑电信号多尺度熵与脑疲劳的关系。方法 8名健康男性志愿者以-15°头低位卧床(HDBR)为模拟失重,+15°头高位卧床(HUBR)为对照,志愿者静息30 min后进行2 h内容为1-back图片记忆匹配VDT作业。结果实验初HDBR条件下志愿者前额区脑电多尺度熵比HUBR条件下高,两种条件下实验末多尺度熵下降显著,HDBR条件下降幅高于HUBR条件下降幅。结论 1)志愿者短期处于模拟失重条件的应激能力会提高;2)志愿者执行长时间脑负荷任务后短时记忆能力下降,HDBR条件下志愿者执行长时间脑负荷作业更易脑疲劳;3)脑电多尺度熵随脑疲劳程度加深而逐渐降低,可用于脑疲劳的监测。
Objective To observe the changes of complexity of EEG during simulated head-ward low bed rest and to investigate the relationship between EEG multiscale entropy and brain fatigue. Methods Eight healthy male volunteers under simulated weightlessness (HDBR) at -15 ° head-rest and HUBR at + 15 ° were used as control. The volunteers were subjected to 2-hour rest after resting for 1 min Match VDT jobs. Results At the beginning of experiment, the EEG multispectral entropy of the forehead in HDBR was higher than that in HUBR. The multiscale entropy decreased significantly at the end of the experiment under HDBR, but decreased more under the condition of HBRR. Conclusions1) The stress ability of volunteers under simulated weightlessness conditions will be increased in short term; 2) The short-term memory ability of volunteers after long-term brain load tasks decrease; ) EEG multiscale entropy decreases gradually with the degree of brain fatigue, which can be used to monitor brain fatigue.