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本文回顾研究了Texas大学联合医院1960～1978年在治疗的12例鼻前庭表皮样癌病人的情况。全部均系男性白人,并皆有不同程度的吸烟史,年龄为48～82岁;平均随访期3年。对病人的初步治疗为:7人手术,3人单独放疗,2人行放疗加手术。单独放疗的3例,1例肿瘤原发灶较为广泛且有颈淋巴结肿大,该例与另一例需要手术治疗和进一步的放疗。但前者死于鼻表皮样癌,另2人在一年内无复发。单用手术的7人,4人术后1～3年无复发迹象;3人需进一步手术与放疗,其中1人已死于本病,另2人尚无复发。采用手术与放疗的2人,虽对肿瘤原发灶实施了该综合疗法与颈廓清术,但都在3年内(从首次确诊开始)死于难控制的区域性颈淋巴结转移。
This article reviews the situation of 12 cases of nasal vestibular epidermoid carcinoma treated in the United University Hospital of Texas University from 1960 to 1978. All were white males, and all had varying degrees of smoking history, aged 48-82 years; the average follow-up period was 3 years. The initial treatment for the patient was: 7 operations, 3 radiotherapy alone, 2 radiotherapy plus surgery. In 3 cases of radiotherapy alone, 1 case of primary tumor was more extensive and there was swelling of cervical lymph nodes. This case and another case required surgery and further radiation therapy. However, the former died of nasal epidermoid carcinoma and the other 2 had no recurrence within one year. There were only 7 patients who had surgery alone, and 4 had no signs of recurrence 1 to 3 years after surgery. Three patients required further surgery and radiotherapy. One of them had died of the disease and the other had no recurrence. Two people who had surgery and radiotherapy performed the combined therapy and neck dissection on the primary tumor, but all died of difficult-to-control regional cervical lymph node metastases within three years (from the first diagnosis).