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梅毒在许多发展中国家呈高度流行,在发达国家社会经济地位较低人群中仍为一重要的公共卫生问题。近年来,由于梅毒的原发损害已成为人类免疫缺陷病毒传播的一种危险因素,因而对梅毒的研究更受人们的重视。目前尚无一种实验室方法可鉴别梅毒病原体-苍白密螺旋体(TP)。遗传学方法和DNA杂交技术不能对此作出鉴别,很少用于株的分型。数种基于单基因的方法用于株的鉴定亦未获成功。
Syphilis is highly prevalent in many developing countries and remains an important public health problem in the less-socio-economically developed countries in developed countries. In recent years, due to the primary damage of syphilis has become a risk factor for the spread of human immunodeficiency virus, so the study of syphilis more people’s attention. No laboratory method currently exists to identify the syphilis pathogen, Treponema pallidum (TP). Genetic methods and DNA hybridization techniques can not be identified, rarely used for strain classification. Several single-gene-based methods have also not been used for strain identification.