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目的探讨幽门螺杆菌(Hp)感染与缺铁性贫血(IDA)的相关性。方法 305例进行13C-尿素呼气试验的患者,其中Hp阳性患者作为观察组,Hp阴性患者作为对照组,上述患者同时进行血常规检测,观察IDA的发生情况,并分析Hp感染与IDA的相关性。结果 305例患者中,Hp检测结果为阳性116例(观察组),Hp检测结果为阴性189例(对照组)。305例患者中,检出IDA 58例,其中轻度IDA 38例,中度IDA 17例,重度IDA 3,无极重度贫血例。观察组IDA发生率为25.86%,高于对照组的14.81%,差异具有统计学意义(P<0.05)。结论 Hp感染可能是IDA的一个致病因素,Hp感染与IDA具有相关性。
Objective To investigate the relationship between Helicobacter pylori (Hp) infection and iron deficiency anemia (IDA). Methods A total of 305 patients undergoing 13C-urea breath test, Hp-positive patients as observation group and Hp-negative patients as control group, were included in this study. Blood samples were taken at the same time to observe the occurrence of IDA. Hp infection was correlated with IDA Sex. Results Of the 305 patients, Hp test was positive in 116 cases (observation group), and Hp test was negative in 189 cases (control group). Of the 305 patients, 58 were diagnosed with IDA, including 38 cases of mild IDA, 17 cases of moderate IDA, severe IDA 3, and severe non-polar anemia. The incidence of IDA in observation group was 25.86%, which was higher than that in control group (14.81%), the difference was statistically significant (P <0.05). Conclusion Hp infection may be a causative factor of IDA, and Hp infection is associated with IDA.