本文介绍了药物制剂中安乃近和扑热息痛的含量测定方法。取含1～15mg 的样品,加10m18 M的硫酸、5 ml 3%的硫酸锌与过量的铁(Ⅲ)氰化钾在35℃恒温水浴上反应15分钟(扑热息痛)或25分钟(安乃近),过量的铁(Ⅲ)氰化钾以碘量法测定。在测定安乃近和扑热息痛混合液时,应在分离之后进行。安乃近溶于水,扑热息痛不溶于水,但在盐酸中于沸水浴上加热30分钟可溶解,结果误差±1.0%。铁(Ⅲ)氰化钾可在中性、碱性或酸性介质中对 This article describes the determination of metamizole and paracetamol in pharmaceutical preparations. Samples containing 1 to 15 mg were added, 10 ml of M sulfuric acid, 5 ml of 3% zinc sulfate and an excess of iron (III) cyanide were incubated in a constant temperature water bath at 35 ° C for 15 minutes (paracetamol) or 25 minutes ), And excess iron (III) cyanide was determined by iodometry. In the determination of metamizuma and paracetamol mixture, should be carried out after the separation. Analgin dissolved in water, paracetamol insoluble in water, but in hydrochloric acid in boiling water bath for 30 minutes soluble, the results of error ± 1.0%. Iron (III) potassium cyanide can be neutral, alkaline or acidic medium pairs