1发病情况贵州省某牛场存栏数4 000余头,2015年12月初开始出现个别牛发病现象,主要表现为精神沉郁、食欲减退,体温升高(41℃~42.5℃),并伴有咳嗽、流涕,个别牛口腔、鼻镜等部位出现水泡。起初怀疑是天气变冷感冒所致,通过加强饲养管理并与抗生素拌料饲喂,病情没有好转,并且逐渐出现死亡现 1 Incidence The number of cattle in a cattle farm in Guizhou Province is more than 4 000. In the beginning of December 2015, some cow diseases began to occur. The main symptoms were depression, loss of appetite, elevated body temperature (41 ℃ -42.5 ℃) and cough , Runny nose, some cattle mouth, nose and other parts appear blisters. Initially suspected of cold weather caused by colds, by strengthening the feeding management and feeding antibiotics, the condition did not improve, and the gradual death of