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目的了解药物滥用对男男性行为者(MSM)高危行为及梅毒/艾滋病病毒(HIV)感染的影响。方法于2010-2015年采用滚雪球法和同伴推动抽样方法,在深圳市共招募3803名MSM为调查对象。采用一对一问卷调查方法收集其社会人口学特征、近二年内药物滥用史、性取向、性角色、性伴数量、安全套使用情况等,采集静脉血5mL进行梅毒螺旋体抗体和抗-HIV检测。趋势检验采用Cochran-Armitage法,分类资料采用卡方检验。结果175名(4.60%)MSM近二年内有药物滥用史,719例(18.91%)梅毒确认阳性,343例(9.02%)HIV确认阳性,179例(4.71%)梅毒合并HIV感染。与无药物滥用者相比,深圳市MSM药物滥用者最近半年内女性性伴数≥2个、肛交性伴数≥5个、口交性伴数≥5个的比例较高,梅毒感染率、HIV感染率以及梅毒合并HIV感染率分别为前者的1.7692倍、1.8226倍和1.9802倍。结论 MSM药物滥用者易发生多性伴、不使用安全套等高危行为,梅毒/HIV感染率高,应开展有针对性的行为干预。
Objectives To understand the impact of drug abuse on high-risk behaviors and syphilis / HIV infection among men who have sex with men (MSM). Methods By means of snowballing method and peer promotion sampling method from 2010 to 2015, a total of 3,803 MSMs were recruited in Shenzhen. One-on-one questionnaires were used to collect the socio-demographic characteristics, history of drug abuse, sexual orientation, sexual role, number of sexual partners and condom use in the past two years. 5 mL of venous blood was collected for detection of Treponema pallidum antibody and anti-HIV. Trend test using Cochran-Armitage method, classification data using chi-square test. Results 175 (4.60%) MSM had a history of drug abuse in the past two years, 719 (18.91%) were positive for syphilis, 343 (9.02%) were HIV positive, and 179 (4.71%) were infected with HIV. Compared with drug abusers, the number of MSM drug abusers in Shenzhen in the last six months was ≥2, the number of anal sex partners was ≥5, and the number of oral sex partners was ≥5. The prevalence of syphilis infection, HIV Infection rate and syphilis combined with HIV infection rates were 1.7692 times the former, 1.8226 times and 1.9802 times. Conclusions MSM drug abusers are prone to have multiple sexual partners, do not use condoms and other high-risk behaviors, and have high rates of syphilis / HIV infection. Targeted behavioral interventions should be conducted.