论文部分内容阅读
半定量RT-PCR检测2型糖尿病大鼠模型脂肪组织脂联素及骨骼肌组织脂联素受体R1 mRNA表达。与正常大鼠比较,糖尿病大鼠骨骼肌组织脂联素受体R1基因表达无改变。糖尿病大鼠血清脂联素水平下降是由脂肪组织脂联素mRNA表达降低引起的,罗格列酮治疗可以使之改善。
Semi-quantitative RT-PCR was used to detect adiponectin and adiponectin receptor R1 mRNA expression in adipose tissue of type 2 diabetic rats. Compared with normal rats, adiponectin receptor R1 gene expression did not change in skeletal muscle of diabetic rats. The decrease of serum adiponectin level in diabetic rats is caused by the decrease of adiponectin mRNA expression in adipose tissue, and rosiglitazone treatment can improve it.