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采用三种疼痛实验模型，观察剂量变化对川乌、白芍配伍前后镇痛作用的影响。结果表明：剂量增大，川乌、白芍配伍前后的镇痛作用和镇痛增效作用也明显增强，剂量与作用有正相关效应。尤其是小剂量配伍组，减少川乌用量后镇痛效果仍强于或等于大剂量单味川乌组。
Three pain models were used to observe the effect of dose changes on the analgesic effects of Chuanwu and Baizhu before and after compatibility. The results showed that the analgesic effect and analgesia and synergism before and after the compatibility of Chuanwu and Baiyu were significantly increased, and there was a positive correlation between dose and effect. Especially in the small-dose combination group, the analgesic effect after reducing the amount of Chuanwu is still stronger than or equal to the large-dose single-flavored Chuanwu group.