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本文描述了大鼠脊髓L_1节段后柱、后索、侧索和前角的诱发电位及其损伤后的变化,并观察了切断L_4、L_5脊神经背、腹根与横断高位颈髓对电位的影响,以进行行电位来源分析。结果可见,上述四个区域的诱发电位基本由早反应三相波和晚反应组成。分别电解损毁这些部位后,电位波幅均普遍降低,晚期反应较早反应降低明显。后柱或后索受损对电位影响最大。局部损毁后可见L_1及T_(13)水平的硬膜上电位改变明显,尤其晚反应减弱、波峰平坦。反应时值与潜伏时未见明显改变。切断L_4脊神经背、腹根后、电位基本消失。去大脑对电位未见明显影响。结果表明,刺激坐骨神经诱发的脊髓电位起源于低位腰段传入神经和脊髓内多通路的兴奋传导,在一定程度上受腹根逆行活动的影响,与大脑及脊髓下行传导束活动无直接联系。脊髓诱发电位的幅度与波形改变可作为脊髓损伤的判断指标之一。
This article describes the changes of evoked potentials and postsynaptic potentials in the posterior column, lateral cords and anterior horn of the L_1 spinal cord in rats and the effect of cutting off the dorsal, ventral and superior cervical spinal cord of the L_4 and L_5 spinal nerves on the potential. For row potential source analysis. The results show that the four regions of the evoked potential basically by the early reaction of three-phase wave and late reaction. Electrolytic damage to these sites, the potential amplitude are generally lower, early reaction decreased significantly early response. Posterior column or posterior cable damage on the potential of the greatest impact. After local damage, it can be seen that the level of L_1 and T_ (13) changes significantly on the epidural potential, especially the late reaction weakened, the peak is flat. No significant change in response time and latency. Cut off L_4 spinal nerve dorsal root, the potential disappeared. To the brain no significant effect on the potential. The results showed that the potentials of spinal cord induced by stimulating sciatic nerve originated from the excitatory conduction of multiple pathways in the afferent nerves and spinal cord of the lower lumbar lobe and were not directly related to the activities of descending tracts of the brain and spinal cord. Spinal cord evoked potential amplitude and waveform changes can be used as a judge index of spinal cord injury.