子宫内膜异位症(EMs)是一种雌激素依赖性疾病,发病率高,可致盆腔疼痛、月经失调和不孕。EMs与不孕的关系相当复杂,EMs女性生殖过程的每个环节均被研究。从卵巢功能障碍着手,阐述EMs导致卵巢功能下降的原因。卵泡形成受损,卵泡质量差,卵巢的破坏,卵巢局部微环境改变,腹腔微环境改变均可引起卵巢功能的受损,从而引起生育功能障碍。因此,纠正病因、改变盆腔微环境对治疗EMs不孕有重要的作用。 Endometriosis (EMs) is an estrogen-dependent disease with a high incidence of pelvic pain, menstrual disorders and infertility. The relationship between EMs and infertility is quite complex, and every aspect of the female reproductive process in EMs has been studied. Starting from ovarian dysfunction, elucidate why EMs cause decreased ovarian function. Follicular damage, poor quality follicles, ovarian destruction, ovarian local microenvironment changes, changes in the peritoneal microenvironment can cause damage to ovarian function, causing fertility dysfunction. Therefore, to correct the cause, change the pelvic microenvironment on the treatment of infertility EMs have an important role.