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目的对比分析未破裂型输卵管妊娠血管内介入治疗与单纯药物治疗的临床价值。方法以临床首次就诊时,检查确诊为未破裂型输卵管妊娠患者46例,分为A、B2组:A组行血管内灌注甲氨蝶呤(MTX)后栓塞治疗;B组行单纯肌肉注射MTX治疗。比较2组的治疗成功率、杀胚率、血β-HCG的变化情况、超声检查的变化情况及输卵管的通畅情况。对其结果进行统计学分析。结果A组22例,成功率为95.45%(21/22),杀胚率为100%(22/22),血β-HCG下降至正常平均为(15.27±4.52)d,B超检查示包块完全吸收时间为(27.95±4.70)d,输卵管造影检查示输卵管通畅率100%(11/11);B组24例,成功率为70.83%(17/24),杀胚率为75%(18/24),血β-HCG下降至正常平均为(18.79±3.99)d,B超检查示包块完全吸收时间为(30.56±5.88)d,输卵管造影检查示输卵管通畅率100%(8/8)。结论血管内介入治疗成功率及杀胚率均较单纯药物治疗为高;血管内介入治疗安全可靠,可作为临床治疗的良好方法。
Objective To compare the clinical value of endovascular treatment with unruptured tubal pregnancy and simple drug therapy. Methods 46 patients with unruptured tubal pregnancy diagnosed as first clinical visit were divided into group A and group B2: group A received intravascular infusion of methotrexate (MTX) before embolization; group B received intramuscular injection of MTX treatment. The success rate of treatment, the rate of killing embryo, the change of blood β-HCG, the changes of ultrasound examination and the tubal patency were compared between the two groups. The results of statistical analysis. Results A group of 22 cases, the success rate was 95.45% (21/22), kill the embryo rate was 100% (22/22), blood β-HCG decreased to normal average (15.27 ± 4.52) d, B ultrasound showed package The complete absorption time of the block was (27.95 ± 4.70) days. The fallopian tube patency was 100% (11/11). In group B, the success rate was 70.83% (17/24) and the rate of killing embryos was 75% (18.79 ± 3.99) d. The B-mode ultrasonography showed the complete absorption time of the mass was (30.56 ± 5.88) d. The fallopian tube patency was 100% (8 / 8). Conclusion The success rate of endovascular interventional therapy and the rate of killing embryos are higher than that of pure drug therapy. Endovascular interventional therapy is safe and reliable, which can be used as a good method for clinical treatment.