Setdb2 restricts dorsal organizer territory and regulates left-right asymmetry through suppressing f

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Summarizing research work partly funded by NSFC,Dr.Chen Zhu of State Key Laboratory of Medical Genomics,Shanghai Institute of Hematology,RuiJin Hospital,Shanghai Jiao Tong University and his research team reported on PNAS in February 2010 their research findings on dorsal organizer. According to their paper,dorsal organizer formation is one of the most critical steps in early embryonic development.Several genes and signaling pathways that positively regulate the dorsal organizer development have been identified;however,little is known about the factor(s) that negatively regulates the or- Summarizing research work partly funded by NSFC, Dr. Chen Zhu State Lab Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, RuiJin Hospital, Shanghai Jiao Tong University and his research team reported on PNAS in February 2010 their research findings on dorsal organizer. to their paper, dorsal organizer formation is one of the most critical steps in early embryonic development. Sequent genes and signaling pathways that positively regulate the dorsal organizer development have been identified; however, little is known about the factor (s) that negatively regulates the or-
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