1例43岁男性患者因发热给予吲哚美辛栓50 mg直肠应用。约20 min后患者出现胸闷气短、呼吸困难,颜面、口唇及四肢末端发绀、端坐呼吸,两肺满布哮鸣音。紧急予吸氧,雾化吸入布地奈德,静脉滴注甲泼尼龙及多索茶碱。血气分析提示呼吸性酸中毒,心电图检查提示急性心肌缺血。予气管插管、呼吸机辅助呼吸。经综合抢救4 d,患者病情渐平稳。 A 43-year-old male patient received indometacin suppository 50 mg rectally for fever. About 20 minutes later, the patient developed chest tightness and shortness of breath, difficulty breathing, facial, lips and extremities cyanosis, sitting and breathing, lungs covered with wheeze. Emergency to oxygen, inhalation of budesonide, intravenous methylprednisolone and doxofylline. Blood gas analysis suggested respiratory acidosis, ECG prompted acute myocardial ischemia. To the tracheal intubation, ventilator-assisted breathing. After 4 days of comprehensive rescue, the patient’s condition gradually stabilized.