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目的探讨山丘型血吸虫病新疫区阻断血吸虫病传播的对策。方法自1996年起,对桃源县有疫水接触史的人群和在疫区放牧的耕牛采用吡喹酮(成人40mg/kg、儿童50mg/kg、耕牛30mg/kg,每年1次)化疗为主,结合易感地带重点灭螺。结果人、畜粪检阳性率从1996年的5.69%、6.76%下降到2005年的0.04%和0。人群间接血凝试验(IHA)阳性率从1996年的7.45%下降到2004年的1.61%。感染螺密度从1997年的0.0036只/0.11m2下降到2005年的0只/0.11m2,从2000年起未查到感染螺。结论在山丘型新疫区桃源县由于人畜传染源流动较少,疫情相对比较封闭,采取以化疗为主结合重点灭螺的对策,可以取得消除传染源阻断血吸虫病传播的效果。
Objective To explore the strategy of blocking the transmission of schistosomiasis in new endemic area of schistosomiasis. Methods Since 1996, praziquantel (adults 40mg / kg, children 50mg / kg, cattle 30mg / kg, once a year) has been used in Taoyuan County, Dominated, combined with susceptible zone focus on snails. As a result, the positive rates of man and livestock droppings dropped from 5.69% and 6.76% in 1996 to 0.04% and 0 in 2005 respectively. The positive rate of indirect hemagglutination test (IHA) decreased from 7.45% in 1996 to 1.61% in 2004. The density of infected spirochetes dropped from 0.0036 /0.11m2 in 1997 to 0 /0.11m2 in 2005 and no infection was detected in 2000. Conclusion In Taoyuan County, a new type of mountainous area, the epidemic situation is relatively closed due to the low flow of animal and animal sources, and the strategy of combating key molluscs with chemotherapy is mainly adopted to eliminate the infection source and block the transmission of schistosomiasis.