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本文较系统地观察了４５例原发性肝癌患者的细胞免疫功能及其影响因素。结果表明肝癌患者的ＬＡＫ活性、ＮＫ活性，ＩＬ－２活性及淋巴细胞转化反应均明显下降；ＡＦＰ及ＨＢｓＡｇ与细胞免疫功能变化无明显关系，但肿瘤大小与细胞免疫功能下降呈正相关。提示肝癌患者细胞免疫功能全面低下，这可能是多种免疫抑制因子共同作用的结果，改善肝癌患者细胞免疫功能可能阻止或延缓肿瘤生长。
This article systematically observed the cellular immune function and its influencing factors in 45 patients with primary liver cancer. The results showed that LAK activity, NK activity, IL-2 activity and lymphocyte transformation were all significantly decreased in patients with hepatocellular carcinoma. AFP and HBsAg had no significant relationship with cellular immune function, but tumor size was positively correlated with decreased cellular immune function. It is suggested that the cellular immune function of liver cancer patients is generally low, which may be the result of a variety of immunosuppressive factors, and improving the cellular immune function of liver cancer patients may prevent or delay tumor growth.