本文报导以3,4-二甲氧基苯乙酸为原料,酰氯化后,与苄基哌嗪缩合为酰胺,以氢化锂铝还原为1-(3,4-二甲氧基苯乙基)-4-苄基哌嗪,最后制成二盐酸盐。药理试验表明本品具有较明显的降压作用。急性降压约为原水平的50%,持续时间为1～2小时。 In this paper, 3,4-dimethoxyphenylacetic acid was used as the starting material. After the acid chloride was chlorinated, it was condensed with benzylpiperazine to form amide, and lithium aluminum hydride was reduced to 1- (3,4-dimethoxyphenethyl) -4-benzylpiperazine, finally made into dihydrochloride. Pharmacological tests show that this product has a more obvious antihypertensive effect. Acute antihypertensive about 50% of the original level, the duration of 1 to 2 hours.