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目的分析77例发热伴血小板减少综合征病例的临床与流行病学特征,为预防与治疗该病提供科学依据。方法采用流行病学描述性分析与个案调查的方法,回顾性收集、分析2010-2013年湖北省广水市发热伴血小板减少综合征77例病例的临床表现、实验室检查、病原学检查、流行病学特征等情况资料。结果77例病例中14例危重型患者死亡,其他63例患者痊愈。病例多为居住在丘陵地区35岁以上的中老年人;发病呈明显季节性,集中在4~10月;病例呈现高度散发,以丘陵地区多见;病原体以新布尼亚病毒为主。本辖区尚未发现人感染人的依据。结论发热伴血小板减少综合征病例是一种可防可治的疾病,只要提高对本病的认识,做到早诊断、早治疗,就能有效降低该病死亡率。
Objective To analyze the clinical and epidemiological characteristics of 77 cases of fever with thrombocytopenia syndrome and provide a scientific basis for prevention and treatment of the disease. Methods The epidemiological descriptive analysis and case investigation methods were used to retrospectively collect and analyze the clinical manifestations, laboratory tests, etiological tests, epidemiology and epidemiology of 77 cases of fever with thrombocytopenia syndrome in Guangshui City, Hubei Province from 2010 to 2013 Medical characteristics and other information. Results Of the 77 cases, 14 critically ill patients died and the other 63 patients were cured. The cases were mostly middle-aged and elderly people living in hilly areas over the age of 35; the incidence was obviously seasonal, concentrated in 4 to 10 months; the cases were highly exuded, more common in hilly areas; the main pathogen to New Bunyan virus. The area has not found the basis of human infection. Conclusions Fever with thrombocytopenia syndrome is a preventable and curable disease. As long as the understanding of this disease is improved and early diagnosis and early treatment are achieved, the mortality of the disease can be effectively reduced.