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１．资料与方法：（１）病例选择：入选１３１例慢性乙型肝炎患者，男９７例，女３４例，平均年龄３５．２岁。入选条件：血清ＨＢｅＡｇ及ＨＢＶ ＤＮＡ阳性；血清总胆红素＜３０μｍｏｌ／Ｌ，ＡＬＴ为正常值上限的２～６倍；无合并症、并发症及重叠感染；入院前半年内未接受
1. Materials and Methods: (1) Case Selection: A total of 131 patients with chronic hepatitis B were enrolled. There were 97 males and 34 females, with an average age of 35.2 years. Selection criteria: Serum HBeAg and HBV DNA positive; serum total bilirubin <30μmol / L, ALT was 2 to 6 times the upper limit of normal; no complications, complications and overlapping infections; did not accept the first six months before admission