论文部分内容阅读
目的分析盐酸氨溴索在呼吸机相关性肺炎预防中的应用价值。方法随机抽取2009年12月~2012年12月喀什地区结核病防治所暨肺科医院内二科就诊并行机械通气呼吸机辅助呼吸的患者112例,所有患者均给予抗感染、气道湿化和纠正水电酸碱平衡紊乱等支持治疗。其中,常规预防组(n=56),患者雾化吸入糜蛋白酶4000 U和生理盐水50 mL,bid;盐酸氨溴索组(n=56),患者在上述基础上静脉注射盐酸氨溴索注射液30 mg,tid。每周统计两组患者的祛痰效果和呼吸机相关性肺炎的发生情况。结果盐酸氨溴索组呼吸机相关肺炎的发生率为17.86%,祛痰总成功率94.64%;常规预防组呼吸机相关肺炎的发生率33.93%,祛痰的总成功率为75.00%,差异有统计学意义(P<0.05)。结论在常规预防的基础上加用盐酸氨溴索,祛痰效果显著,呼吸机相关性肺炎的发生率明显降低。
Objective To analyze the value of ambroxol hydrochloride in the prevention of ventilator-associated pneumonia. Methods A total of 112 patients with concurrent ventilator-assisted respiration in the Second Hospital of Kashi Prefecture from December 2009 to December 2012 in Kashi Prefecture were enrolled. All patients were given anti-infective, airway humidification and correction Hydropower acid-base balance disorders such as supportive treatment. Among them, patients in routine prevention group (n = 56), patients with inhalation of chymase 4000 U and saline 50 mL, bid; ambroxol hydrochloride group (n = 56), patients on the basis of intravenous injection of ambroxol hydrochloride Liquid 30 mg, tid. The expectant effect and ventilator-associated pneumonia in both groups were statistically analyzed weekly. Results The incidence of ventilator-associated pneumonia in ambroxol hydrochloride group was 17.86%, the total success rate of expectorant was 94.64%. The incidence of ventilator-associated pneumonia in conventional prevention group was 33.93%, and the total success rate of expectorant was 75.00% Statistical significance (P <0.05). Conclusion Ambroxol hydrochloride is added on the basis of routine prevention. The expectorant effect is significant, and the incidence of ventilator-associated pneumonia is significantly reduced.