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对17例并发急性下呼吸道感染的慢性用塞性肺病(COPD)患者进行了营养状态评定和血浆游离氨基酸测定。本组患者在感染时和感染控制后的理想体重百分比(%IBW)分别为85.33±7.02和87.74±7.25,亮氨酸、缬氨酸、精氨酸、丙氨酸和组氨酸等含量在感染控制后明显升高,支链氨基酸/芳香氨基酸比值(BCAA/AAA)与%IBW之间存在显著相关性。结果表明,COPD患者并发急性下呼吸道感染时可促使营养不良更趋恶化,而BCAA/AAA可作为评定COPD营养状态的一种重要指标推荐应用。
Twenty-seven patients with chronic obstructive pulmonary disease (COPD) complicated by acute lower respiratory tract infection were assessed for nutritional status and plasma free amino acids. The ideal body weight percentage (% IBW) at infection and infection control in this group were 85.33 ± 7.02 and 87.74 ± 7.25, respectively, with leucine, valine, arginine and ammonia The contents of acid and histidine were significantly increased after infection control. There was a significant correlation between BCAA / AAA and% IBW. The results show that COPD patients with acute lower respiratory tract infection can promote malnutrition worsened, and BCAA / AAA can be used as a measure of nutritional status of COPD is an important indicator of recommended.