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为比较肾综合征出血热Ⅰ型灭活疫苗接种组和对照组免疫后 4年的抗体水平 ,1997年 11月～ 1998年 7月在浙江省建德市肾综合征出血热Ⅰ型灭活疫苗随机对照试验现场 ,分别采集接种组和对照组双份血清 2 95人和 2 68人 ,检测血清中间接荧光抗体。按血清间接荧光抗体阳性或阴性来比较接种组和对照组的抗体水平 ,均未见接种组和对照组有显著差异。接种组同对照组免疫后 4年抗体水平无显著性差异 ,未见肾综合征出血热Ⅰ型灭活疫苗增强接种人群发生隐性感染。
In order to compare the antibody level of 4 years after immunization with type I inactivated vaccine of hemorrhagic fever with renal syndrome and the control group, the type I inactivated vaccine of hemorrhagic fever with renal syndrome of renal syndrome in Jiande, Zhejiang Province from November 1997 to July 1998 Randomly controlled trial site, respectively, vaccinated group and control group were seized 2 95 serum samples and 2 68 people, serum indirect fluorescent antibody was detected. Antibody levels in vaccinated and control groups were compared by indirect or indirect fluorescent antibody sera, and no significant differences were observed between vaccinated and control groups. There was no significant difference in antibody level between the inoculated group and the control group at 4 years after immunization, and no inactivated infection with type I inactivated vaccine of renal syndrome hemorrhagic fever was found.