该文根据难治性溃疡的病理生理特点，采用中西医结合的方法（即内镜下局部清创加中药喷洒的方法），治疗了８６例难治性溃疡，并对治疗结果进行了总结分析；同时与口服药物治疗难治性溃疡进行了比较对照。其结果证明：该疗法疗效高，疗程短，无副作用，安全可靠，在难治性溃疡尚无理想治疗方法的情况下，具有实际应用价值。 According to the pathophysiological characteristics of refractory ulcer, 86 cases of refractory ulcer were treated with the method of integrated traditional Chinese and western medicine (ie endoscopic debridement plus traditional Chinese medicine spraying), and the treatment results were summarized ; At the same time with oral medication for treatment of refractory ulcer were compared. The results show that: The high efficacy of the therapy, short course of treatment, no side effects, safe and reliable, refractory ulcer in the absence of an ideal treatment of cases, has practical value.