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250例肝细胞癌的非癌部位进行超声显像、手术、病理对照研究显示:90%的肝细胞癌(Hepatocellularcarcinoma,HCC)发生在HBV阳性的结节性肝硬化声像图背景,其中54%和36%分别发生在大结节性和小结节性肝硬化中;6例大结节性肝硬化病例,B超追踪过程中进展为HCC,均未发生在肝表面最大再生结节,其中2例发生癌结节前仅表现为小片状及几个光点聚集成簇的强回声区,细胞学检查提示有细胞异型增生,后继续追踪过程中癌结节显现。结果表明:超声显像支持HCC是由肝硬化进展而来这一观点,但最大的再生结节不一定是HCC的癌前病变;硬化肝实质中出现小片状或粗大光点成簇时,及时进行穿刺组织学检查可能发现癌前病变区或对早早期HCC作出诊断。
Ultrasonographic, surgical, and pathological control studies of 250 non-cancerous parts of hepatocellular carcinoma showed that 90% of hepatocellular carcinoma (HCC) occurred in the background of HBV-positive nodular liver cirrhosis, and 54% of them And 36% occurred in large nodular and nodular cirrhosis; 6 cases of large nodular liver cirrhosis, progress to HCC in the B-tracking process, none occurred in the largest regenerative nodule on the liver surface, including Two cases of precancerous lesions showed only a few patches and a few echoes clustered into a strong echogenic area. Cytological examination revealed dysplasia, and nodules appeared during follow-up. The results show that: ultrasound imaging supports the view that HCC is derived from the progression of liver cirrhosis, but the largest regenerating nodule is not necessarily the precancerous lesion of HCC; when small pieces or thick light spots are clustered in the hardened liver parenchyma, Prompt puncture histological examination may find precancerous lesions or diagnose early HCC.