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目的:研究对宫颈癌根治术麻醉后患者采用右美托咪啶对其早期认知功能影响的效果。方法:以2013年8月~2015年8月进行宫颈癌根治术60例患者为研究对象,随机分成治疗组与对照组。在麻醉诱导后分别给予对照组、治疗组等量生理盐水和右美托咪啶。比较两组使用麻黄碱和阿托品的情况以及MMSE评分。结果:两组患者麻黄碱使用量相近,P>0.05,差异无统计学意义,治疗组患者阿托品使用量以及术后6 h、1d、2 d时MMSE评分高于对照组,以上指标对比,P<0.05,差异有统计学意义。结论:对宫颈癌根治术麻醉后患者采用右美托咪啶对其早期认知功能障碍具有明显改善作用,适合推广应用。
Objective: To study the effect of dexmedetomidine on early cognitive function in patients with cervical cancer after radical operation. Methods: From August 2013 to August 2015, 60 patients with cervical cancer radical mastectomy were randomly divided into treatment group and control group. After the induction of anesthesia were given to the control group, the treatment group, the same amount of saline and dexmedetomidine. The use of ephedrine and atropine in both groups was compared with MMSE scores. Results: There was no significant difference in the amount of ephedrine between the two groups (P> 0.05). The amount of atropine used in the treatment group and MMSE score at 6 h, 1 d, and 2 d after operation were higher than those in the control group. P <0.05, the difference was statistically significant. Conclusion: The use of dexmedetomidine in patients with cervical cancer after radical anesthesia has obvious improvement on its early cognitive dysfunction and is suitable for popularization and application.