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目的:观察卡孕栓联合缩宫素用于疤痕子宫二次剖宫产术后的止血效果。方法:88例疤痕子宫二次剖宫产妇随机分为两组,对照组产妇单用缩宫素治疗,联合组产妇采用卡孕栓联合缩宫素治疗。统计两组患者术中、术后出血量,术后血压和术中凝血功能指标,并统计产妇控制出血措施和术后不良反应情况。结果:联合组产妇的产后出血发生率明显低于对照组产妇(P<0.05),术中、术后2 h和术后24 h出血量均明显少于对照组产妇(P<0.05)。两组产妇术后血压比较差异无统计学意义(P>0.05),术中凝血功能指标比较,差异有统计学意义(P<0.05)。联合组产妇术中术后采用子宫按摩、手术和使用药物止血措施的例数均明显少于对照组产妇(P<0.05)。两组产妇不良反应发生率比较,差异无统计学意义(P>0.05)。结论:卡孕栓联合缩宫素可有效减少疤痕子宫二次剖宫产术后出血,效果显著,安全性高。
Objective: To observe the effect of carbamazepine combined with oxytocin on hemostasis after secondary cesarean section of scar tissue. Methods: 88 cases of secondary uterine cesarean scar were randomly divided into two groups. The control group was treated with oxytocin alone. The combined group was treated with carbamazepine and oxytocin. The intraoperative and postoperative blood loss, postoperative blood pressure and intraoperative coagulation parameters were calculated. The measures of maternal bleeding control and postoperative adverse reactions were also calculated. Results: The incidence of postpartum hemorrhage in the combined group was significantly lower than that in the control group (P <0.05). The intraoperative, postoperative 2 h and 24 h postoperative bleeding were significantly less than those in the control group (P <0.05). There was no significant difference in postoperative blood pressure between the two groups (P> 0.05). There was significant difference in coagulation function between the two groups (P <0.05). The combined group of maternal postoperative hysterectomy, surgery and the use of drugs to stop the bleeding cases were significantly less than the control group maternal (P <0.05). Two groups of maternal adverse reactions, the difference was not statistically significant (P> 0.05). Conclusion: The combination of carbamazepine and oxytocin can effectively reduce the bleeding after secondary cesarean section in patients with scars and uterus. The results are significant and safe.