论文部分内容阅读
本研究旨在评价癫痫患者在接受药酶诱导性抗癫痫药物（AEDs）治疗的同时，拉莫三嗪（LTG）逐渐加大剂量至S77twd时的耐受性和安全性，并确定该药剂量在）ANndd时的药代动力学模型。方法本研究为随机双喜安慰剂对照同步试验。试验全程包括2周基础筛检期、两个连续的3周治疗期（
The purpose of this study was to evaluate the tolerability and safety of lamotrigine (LTG) in increasing doses to S77twd while receiving the enzyme-inducible antiepileptic drugs (AEDs) in patients with epilepsy and to determine the dose Pharmacokinetic model at ANndd. Methods This study was randomized double happiness placebo-controlled trial. The trial included 2 weeks of basic screening, two consecutive 3 weeks of treatment (