柱晶白霉素是从链丝菌S.kitesatoer-sis中产生的大环内酯类抗生素。对革蓝氏阳性、阴性菌,立克次氏体,螺旋体及病毒有较强的抑制作用。毒副反应小,无大环内酯类抗生素所引起的肝肿大、SGPT升高等肝功障碍。现将我所新抗室研制的柱晶白霉素洒石酸盐体外抗菌活力及体内急性、亚急性毒性实验结果报告如下: 实验结果表明:一、柱晶白霉素主要是抗革蓝氏阳性菌,对革蓝氏阴性菌的活力低。对金黄色葡萄球菌、溶血性链球菌、肠球菌、化脓 Leucomalamin is a macrolide antibiotic produced from Streptomyces S. kitesatoer-sis. Gram-positive, negative bacteria, rickettsia, spirochetes and viruses have a strong inhibitory effect. Toxic side effects, no macrolide antibiotics caused by hepatomegaly, SGPT increased liver function disorders. Now I developed a new anti-room column leucoamycin in vitro antibacterial vitality and in vivo acute, subacute toxicity test results are reported as follows: The experimental results show that: First, columnar leuromycin is mainly anti-leather blue Positive bacteria, low activity against gram-negative bacteria. Staphylococcus aureus, hemolytic streptococcus, enterococci, purulent