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INTRODUCTIONThe etiopathogenesis of ulcerative colitis (UC)remains obscure,due to lack of an ideal animalmodel.With thc improvement of theory andmethodology in the last 30 years,people used toadopt chemicals(acetic acid,ethanol,carrageen,etc.),immunotechniques(humoral or cellularimmunity,immune complex) and substance derivedfrom UC patients to set up various kinds of UCanimal model,which mimic the pathologic changesof human UC,so far these remain far from
INTRODUCTIONThe etiopathogenesis of ulcerative colitis (UC) remains obscure, due to lack of an ideal animal model. Thith improvement of theory and methodology in the last 30 years, people used toadopt chemicals (acetic acid, ethanol, carrageen, etc.), Immunotechniques or cellularimmunity, immune complex) and substance derived from UC patients to set up various kinds of UCanimal model, which mimic the pathologic changes of human UC, so far these remain far from