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目的:了解2岁幼儿锌的吸收率(fractionalzincabsorption,FAZ)以及实际吸收的锌总量(totalabsorbedzinc,TAZ)。方法:运用双稳定同位素标记法,口服并静脉注射两种稳定同位素,由尿液中同位素的丰度得到膳食锌的吸收率;测定食物中的锌含量并计算实际吸收的锌总量。共有43名19～25月龄的健康幼儿参加实验。其中21名幼儿(女12,男9)来自贫困乡村地区;另22名幼儿(女12,男10)来自相邻的城镇,两组幼儿的膳食均以米饭和蔬菜为主,城镇组幼儿包括部分动物性食物。结果:乡村组和城镇组幼儿膳食锌的摄入量分别为1.91±0.59和1.81±0.52mg/d;锌的吸收率为0.33±0.10和0.37±0.14mg/d;两组幼儿实际的锌吸收量为0.63±0.28和0.64±0.20mg/d。两组间以及男、女幼儿间均无任何差异。结论:参加实验幼儿每天从膳食中实际吸收的锌总量低于美国FNB(FoodandNutritionBoard);IDM(InstituteofMedicine)2001年公布的1～3岁幼儿锌的生理需要量0.744mg/d,实验地区幼儿身高不足比较普遍,两组幼儿血浆锌水平偏低,分别为10.08±0.13,10.02±0.13μmol/L,提示受试幼儿的锌营养状况处于边缘缺乏水平。
OBJECTIVE: To investigate the fractional zinc absorption (FAZ) of 2-year-old infants and the total amount of zinc absorbed (TAZ). Methods: Bistable isotope labeling method was used to orally and intravenously inject two kinds of stable isotopes to get the absorption rate of dietary zinc from the abundance of the isotopes in the urine. The content of zinc in food was measured and the amount of zinc actually absorbed was calculated. A total of 43 healthy children 19 to 25 months of age participated in the experiment. Twenty-one of the 21 young children (12 women and 9 men) came from poor rural areas. The other 22 children (12 women and 10 men) came from adjacent towns. The meals of the two groups were mostly rice and vegetables. The children of urban group included Part of animal food. Results: Dietary zinc intake in rural and urban groups was 1.91 ± 0.59 and 1.81 ± 0.52 mg / day, respectively, and the zinc absorption rates were 0.33 ± 0.10 and 0.37 ± 0.14 mg / day. The actual zinc absorption The quantities were 0.63 ± 0.28 and 0.64 ± 0.20 mg / d. There was no difference between the two groups and between male and female children. Conclusion: The total amount of zinc actually absorbed by the young children from the diet per day was lower than that of the FNB (Foodand Nutrition Board) in the United States. The physical requirement of zinc for children aged 1-3 years old published by the Institute of Medicine (IDM) in 2001 was0.744mg / d, The insufficiency was more common. The levels of plasma zinc in the two groups were low, 10.08 ± 0.13 and 10.02 ± 0.13μmol / L, respectively, suggesting that the nutritional status of zinc in young children was marginal.